730300

Methacrylic acid N-hydroxysuccinimide ester

98%

• Sinónimos: N-(Methacryloxy)succinimide, N-(Methacryloyloxy)succinimide
• Fórmula empírica (notación de Hill): C₈H₉NO₄
• Número de CAS: 38862-25-8
• Peso molecular: 183.16
• Número MDL: MFCD15072193
• Código UNSPSC: 12162002
• ID de la sustancia en PubChem: 329764554
• NACRES: NA.23

Propiedades

• Nivel de calidad: 100
• Análisis: 98%
• formulario: solid
• mp: 101-105 °C
• temp. de almacenamiento: 2-8°C
• cadena SMILES: CC(=C)C(=O)ON1C(=O)CCC1=O
• InChI: 1S/C8H9NO4/c1-5(2)8(12)13-9-6(10)3-4-7(9)11/h1,3-4H2,2H3
• Clave InChI: ACGJEMXWUYWELU-UHFFFAOYSA-N

Descripción

Descripción general

Methacrylic acid N-hydroxysuccinimide ester(NHS-MA) belongs to the class of reactive monomers known as N-hydroxysuccinimide (NHS) esters. It is commonly used for functionalizing biomolecules through amine-reactive coupling reactions infields such as bioconjugation, protein labeling, and peptide synthesis. It also serves as a crosslinking agent or linker molecule for the conjugation of drugs or targeting ligands to carrier materials.

Aplicación

Methacrylic acid N-hydroxysuccinimide ester can be used:

• As a monomer to prepare degradable amphiphilic diblock copolymer microparticles via RAFT polymerization, for low pH-triggered drug delivery. NHS-MA can shield the drug molecule from degradation, enhance its solubility, and improve its pharmacokinetic properties.
• For the surface functionalization of poly-ε-caprolactone (PCL) scaffolds used for tissue engineering. NHS groups are used to couple with chitosan of various molecular weights.
• To prepare biocompatible polymer hydrogel for enzymatic biofuel cells. The hydrogel can serve as an enzyme-immobilizing matrix for enzymatic bioelectrodes.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302 + H332,H315,H317,H319,H335
• Consejos de prudencia: P261 - P280 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 4 Inhalation - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Órganos de actuación: Respiratory system
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable