698121

4-Iodophenylboronic acid MIDA ester

97%

• Sinónimos: 2-(4-Iodophenyl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione
• Fórmula empírica (notación de Hill): C₁₁H₁₁BINO₄
• Número de CAS: 1257649-56-1
• Peso molecular: 358.92
• Número MDL: MFCD11215234
• Código UNSPSC: 12352103
• ID de la sustancia en PubChem: 329761984
• NACRES: NA.22

Propiedades

• Análisis: 97%
• formulario: solid
• mp: 213-217 °C
• cadena SMILES: CN1CC(=O)OB(OC(=O)C1)c2ccc(I)cc2
• InChI: 1S/C11H11BINO4/c1-14-6-10(15)17-12(18-11(16)7-14)8-2-4-9(13)5-3-8/h2-5H,6-7H2,1H3
• Clave InChI: KIKNJEGAWBNFLW-UHFFFAOYSA-N

Descripción

Aplicación

Suzuki Cross-Coupling with MIDA Boronates

4-Iodophenylboronic acid MIDA ester can be used:

• As a starting material to prepare rod-like hydrogen-bonded organic frameworks through Stille-coupling using 2,5-bis(trimethyltin)heterocycle, Pd(PPh₃)₄, and CuI.
• As a substrate in the C-H arylation reaction of pyroglutamic acid derivatives with aryl and heteroaryl iodides; catalyzed by the palladium catalyst.
• As a substrate in the synthesis of trifluoroborates, which are further converted to protected boronic acids.
• As a starting material in the synthesis of amino acid MIDA boronates as new building blocks by reacting with protected iodoalanine.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302
• Clasificaciones de peligro: Acute Tox. 4 Oral
• Código de clase de almacenamiento: 13 - Non Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves