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Merck

291196

Sigma-Aldrich

Creatine

98%

Sinónimos:

(α-Methylguanido)acetic acid, N-Amidinosarcosine

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About This Item

Fórmula lineal:
H2NC(=NH)N(CH3)CH2CO2H
Número de CAS:
Peso molecular:
131.13
Beilstein:
907175
Número CE:
Número MDL:
Código UNSPSC:
12352200
ID de la sustancia en PubChem:

Ensayo

98%

cadena SMILES

CN(CC(O)=O)C(N)=N

InChI

1S/C4H9N3O2/c1-7(4(5)6)2-3(8)9/h2H2,1H3,(H3,5,6)(H,8,9)

Clave InChI

CVSVTCORWBXHQV-UHFFFAOYSA-N

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Acciones bioquímicas o fisiológicas

Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP.
Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine supplementation is used for the enhancement of sports performance, primarily by increasing muscle mass. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.

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This review discusses the various causes of primary hypersomnias with emphasis on clinical recognition, diagnosis, and treatment options. Narcolepsy is probably the most fascinating syndrome causing excessive daytime sleepiness. With increasing understanding of the hypocretin/orexin pathways and the neurotransmitters that
Creatine--a dispensable metabolite?
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The creatine transporter deficiency is a neurological disease caused by impairment of the creatine transporter SLC6A8, resulting in mental retardation associated with a complete absence of creatine within the brain and cellular energy perturbation of neuronal cells. One of the

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