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Merck

PTGDR

prostaglandin D2 receptor (DP)

Sinónimos:
AS1, ASRT1, DP, DP1, PTGDR1
Especie:
Human PTGDR (5729), Mouse Ptgdr (19214), Rat Ptgdr (498475), naked mole-rat Ptgdr (101710975), domestic cat PTGDR (101098059), cow PTGDR (515331), dog PTGDR (610845), domestic guinea pig Ptgdr (100721994)
ID UniProtKB:
Q13258, Q13250, Q13251, Q1ZZ52
ID del gen:
  • Human(5729) Summary: The protein encoded by this gene is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses. [provided by RefSeq, Jul 2008]
  • Mouse(19214) prostaglandin D receptor
  • Rat(498475) prostaglandin D2 receptor-like
  • naked mole-rat(101710975) prostaglandin D2 receptor (DP)
  • domestic cat(101098059) prostaglandin D2 receptor (DP)
  • cow(515331) prostaglandin D2 receptor (DP)
  • dog(610845) prostaglandin D2 receptor (DP)
  • domestic guinea pig(100721994) prostaglandin D2 receptor (DP)

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Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
I7378
Indomethacin, 98.5-100.5% (in accordance with EP),
Especie
human, mouse, rat
I8280
Indomethacin, meets USP testing specifications,
Especie
human, mouse, rat

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
SAB1406332
Anti-PTGDR antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
flow cytometry
western blot
HPA049668
Anti-PTGDR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
SAB1401319
Anti-PTGDR antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
SAB4502478
Anti-PTGDR antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence
western blot
HPA046586
Anti-Ptgdr Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot

Small Molecule - Mixed Agonist/Antagonist

Referencia del producto
Descripción
Especie
I7378
Indomethacin, 98.5-100.5% (in accordance with EP),
Especie
human, mouse, rat

Proteins

Referencia del producto
Descripción
Especie
HTS091M
ChemiSCREEN Human DP Prostanoid Receptor Membrane Preparation, Human DP GPCR membrane preparation for Radioligand binding Assays & GTPgammaS binding.,
Especie
human