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Merck

POLD1

polymerase (DNA directed), delta 1, catalytic subunit

Sinónimos:
CDC2, CRCS10, MDPL, POLD
Especie:
Human POLD1 (5424), Mouse Pold1 (18971), Rat Pold1 (59294), naked mole-rat Pold1 (101699680), domestic cat POLD1 (101086519), domestic guinea pig Pold1 (100719673), Horse POLD1 (100052455), Zebrafish pold1 (556456), cow POLD1 (281990), sheep POLD1 (101117012)
ID UniProtKB:
P28340, Q8NER3, Q96H98
ID del gen:
  • Human(5424) Summary: This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Mar 2012]
  • Mouse(18971) polymerase (DNA directed), delta 1, catalytic subunit
  • Rat(59294) polymerase (DNA directed), delta 1, catalytic subunit
  • naked mole-rat(101699680) polymerase (DNA directed), delta 1, catalytic subunit
  • domestic cat(101086519) polymerase (DNA directed), delta 1, catalytic subunit
  • domestic guinea pig(100719673) polymerase (DNA directed), delta 1, catalytic subunit
  • Horse(100052455) polymerase (DNA directed), delta 1, catalytic subunit
  • Zebrafish(556456) polymerase (DNA directed), delta 1, catalytic subunit
  • cow(281990) polymerase (DNA directed), delta 1, catalytic subunit
  • sheep(101117012) polymerase (DNA directed), delta 1, catalytic subunit
  • dog(610047) polymerase (DNA directed), delta 1, catalytic subunit

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
SAB4200053
Anti-DNA polymerase δ p125 antibody, Rat monoclonal, clone PDG 5G1, purified from hybridoma cell culture,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
immunoprecipitation (IP)
western blot
MABE967
Anticuerpo anti-ADN polimerasa delta p125, clon 11E10.1, clone 11E10.1, from mouse,
Reactividad de especies
human
Aplicación
western blot
HPA046524
Anti-POLD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
SAB4502237
Anti-POLD1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
western blot
SAB2702144
Monoclonal Anti-POLD1 antibody produced in mouse, ,
Reactividad de especies
human, mouse
Aplicación
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
A0781
Aphidicolin from Nigrospora sphaerica, ≥98% (HPLC), powder,
Especie
human
P6801
Sodium phosphonoformate tribasic hexahydrate, ,
Especie
rat, human
C6645
Cytosine β-D-arabinofuranoside hydrochloride, crystalline,
Especie
human
1162002
Cytarabine, United States Pharmacopeia (USP) Reference Standard,
Especie
human
C3350000
Cytarabine, European Pharmacopoeia (EP) Reference Standard,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU131101
MISSION® esiRNA, targeting human POLD1,
Especie
human
EMU016741
MISSION® esiRNA, targeting mouse Pold1,
Especie
mouse