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Merck

PIK3R1

phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Sinónimos:
AGM7, GRB1, p85, p85-ALPHA
Especie:
Human PIK3R1 (5295), Mouse Pik3r1 (18708), Rat Pik3r1 (25513), domestic guinea pig Pik3r1 (100730242), domestic cat PIK3R1 (100271864), cow PIK3R1 (282307), sheep PIK3R1 (101121455), chicken PIK3R1 (427171), Zebrafish pik3r1 (557176), dog PIK3R1 (487235)
ID UniProtKB:
P27986, B3KT19, D3DWA0, E7EX19, Q15747, Q4VBZ7, Q53EM6, Q8IXA2
ID del gen:
  • Human(5295) Summary: Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
  • Mouse(18708) phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
  • Rat(25513) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • domestic guinea pig(100730242) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • domestic cat(100271864) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • cow(282307) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • sheep(101121455) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • chicken(427171) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  • Zebrafish(557176) phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)
  • dog(487235) phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
05-212
Anti-PI3 Kinase Antibody, p85, N-SH3, clone AB6, clone AB6, Upstate®, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
immunoprecipitation (IP)
western blot
SAB4504315
Anti-phospho-PI3-kinase p85-α (pTyr607) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry
western blot
SAB4504314
Anti-phospho-PI3-kinase p85-α/γ (pTyr467/199) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
western blot
SAB5500162
Anti-PI3K P85 antibody, Rabbit monoclonal, clone SP62, recombinant, expressed in proprietary host, affinity isolated antibody,
Reactividad de especies
bovine, frog, human, mouse, rat
Aplicación
flow cytometry
immunohistochemistry
ABS1856
Anti-PI3 Kinase Antibody, p85, from rabbit, purified by affinity chromatography,
Reactividad de especies
bovine, human, mouse, rat, rhesus monkey
Aplicación
immunoprecipitation (IP)
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
W1628
Wortmannin, from Penicillium funiculosum, ≥98% (HPLC and TLC),
Especie
human
W3144
Wortmannin, Ready Made Solution, from Penicillium funiculosum, ≥95% (HPLC),
Especie
human
D2926
Diphenyleneiodonium chloride, ≥98%,
Especie
mouse, human
PZ0235
PF-04691502, ≥98% (HPLC),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EMU187151
MISSION® esiRNA, targeting mouse Pik3r1,
Especie
mouse
EHU151811
MISSION® esiRNA, targeting human PIK3R1,
Especie
human