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Merck

PIK3CB

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

Sinónimos:
P110BETA, PI3K, PI3KBETA, PIK3C1
Especie:
ID UniProtKB:
ID del gen:
  • Human(5291) Summary: This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
  • Mouse(74769) phosphatidylinositol 3-kinase, catalytic, beta polypeptide
  • Rat(85243) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
  • dog(477085) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
  • naked mole-rat(101715249) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
  • domestic cat(101091892) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
  • sheep(101109759) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
  • cow(517948) phosphoinositide-3-kinase, catalytic, beta polypeptide
  • Zebrafish(100002263) phosphoinositide-3-kinase, catalytic, beta polypeptide
  • chicken(424826) phosphoinositide-3-kinase, catalytic, beta polypeptide
  • Horse(100051753) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
  • Domestic Rabbit(100345181) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
  • domestic guinea pig(100727986) phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PI3 Kinase Antibody, p110β, from rabbit, purified by affinity chromatography,
Reactividad de especies
canine, dog, human, monkey, mouse, rat
Aplicación
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-PI3 Kinase p110 β Antibody, clone 1D18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey, porcine
Aplicación
affinity binding assay
immunohistochemistry

western blot
Anti-PIK3CB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
Monoclonal Anti-PIK3CB antibody produced in mouse, clone 10D5, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence

proximity ligation assay

western blot
Anti-PIK3CB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
PF-04691502, ≥98% (HPLC),
Especie
human

Proteins

Referencia del producto
Descripción
Especie
PI3K (p110-β/p85-β), active, His tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
PI3 Kinase (p110β/p85β) Murine, 250 µg, ,
Especie
mouse
PI3 Kinase (p110β/p85β) Murine, 10 µg, ,
Especie
mouse

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PIK3CB,
Especie
human
MISSION® esiRNA, targeting mouse Pik3cb,
Especie
mouse