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Merck

PDGFRB

platelet-derived growth factor receptor, beta polypeptide

Sinónimos:
CD140B, IBGC4, IMF1, JTK12, PDGFR, PDGFR-1, PDGFR1
Especie:
Human PDGFRB (5159), Mouse Pdgfrb (18596), Rat Pdgfrb (24629), domestic guinea pig Pdgfrb (100726506), naked mole-rat Pdgfrb (101721151), Zebrafish pdgfrb (559529), chicken PDGFRB (770488), dog PDGFRB (442985), domestic cat PDGFRB (101084600), cow PDGFRB (527165) ...Más
ID UniProtKB:
P09619, Q8N5L4
ID del gen:
  • Human(5159) Summary: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008]
  • Mouse(18596) platelet derived growth factor receptor, beta polypeptide
  • Rat(24629) platelet derived growth factor receptor, beta polypeptide
  • domestic guinea pig(100726506) platelet-derived growth factor receptor, beta polypeptide
  • naked mole-rat(101721151) platelet-derived growth factor receptor, beta polypeptide
  • Zebrafish(559529) platelet-derived growth factor receptor beta
  • chicken(770488) platelet-derived growth factor receptor, beta polypeptide
  • dog(442985) platelet-derived growth factor receptor, beta polypeptide
  • domestic cat(101084600) platelet-derived growth factor receptor, beta polypeptide
  • cow(527165) platelet-derived growth factor receptor, beta polypeptide
  • Domestic Rabbit(100342872) platelet-derived growth factor receptor, beta polypeptide
  • sheep(101122783) platelet-derived growth factor receptor, beta polypeptide

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ELISA

Referencia del producto
Descripción
Especie
RAB0400
Human PDGF R β ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Especie
human
RAB1858
Mouse PDGF-BB ELISA, for serum, plasma and cell culture supernatants,
Especie
mouse
RAB0985
Phosphotyrosine PDGFRB / Platelet-derived Growth Factor Receptor Beta ELISA Kit, ,
Especie
human
RAB1824
Rhesus Macaque PDGF R beta ELISA, for serum, plasma and cell culture supernatants,
Especie

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
SAB5702167
Anti-PDGFRB Antibody, clone 6E8C10, Rabbit Monoclonal, ,
Reactividad de especies
mouse
Aplicación
immunofluorescence
western blot
SAB4502149
Anti-PDGF Receptor β antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
immunohistochemistry
western blot
HPA028499
Anti-PDGFRB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
SAB4502148
Anti-PDGFR β antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence
immunohistochemistry
western blot
05-1135
Anticuerpo anti-PDGFR, clon CH-3, clone CH-3, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
P19809
2-Phenylbenzimidazole, 97%,
Especie
human
CDS022173
Imatinib, ,
Especie
human
S8442
SU 5416, ≥98% (HPLC),
Especie
human, mouse
T182
Tyrphostin A9, solid,
Especie
mouse, human
CDS023580
Pazopanib, ,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
14-463-M
PDGFRβ Protein, active, 50 µg, Active, recombinant human PDGF Receptor β, residues 557-end, containing an N-terminal His6-tag, for use in Kinase Assays.,
Especie
human
SRP0351
PDGFRb active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Especie
human
G8671
PDGFRβ(557-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU051271
MISSION® esiRNA, targeting human PDGFRB,
Especie
human