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Merck

MTNR1A

melatonin receptor 1A

Sinónimos:
MEL-1A-R, MT1
Especie:
ID UniProtKB:
ID del gen:
  • Human(4543) Summary: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008]
  • Mouse(17773) melatonin receptor 1A
  • Rat(114211) melatonin receptor 1A
  • dog(482904) melatonin receptor 1A
  • sheep(443022) melatonin receptor 1A
  • chicken(396319) melatonin receptor 1A
  • naked mole-rat(101719975) melatonin receptor 1A
  • domestic guinea pig(100720785) melatonin receptor 1A
  • cow(539948) melatonin receptor 1A
  • domestic cat(101098297) melatonin receptor 1A

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
6-Hydroxymelatonin, ,
Especie
human
Ramelteon, ,
Especie
human
Agomelatine, ≥98% (HPLC),
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Luzindole, ≥90%,
Especie
human
Agomelatine, ≥98% (HPLC),
Especie
human
Melatonina, powder, ≥98% (TLC),
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-MTNR1A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
Melatonina, powder, ≥98% (TLC),
Especie
human

Small Molecule - Precursor

Referencia del producto
Descripción
Especie
N-Acetyl-5-hydroxytryptamine, ≥99% (HPLC), powder,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
ChemiSCREEN Membrane Preparation Recombinant Human MT1 Melatonin Receptor, ,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human MTNR1A,
Especie
human