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Merck

KCNA5

potassium voltage-gated channel, shaker-related subfamily, member 5

Sinónimos:
ATFB7, HCK1, HK2, HPCN1, KV1.5, PCN1
Especie:
ID UniProtKB:
ID del gen:
  • Human(3741) Summary: Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7). [provided by RefSeq, May 2012]
  • Mouse(16493) potassium voltage-gated channel, shaker-related subfamily, member 5
  • Rat(25470) potassium voltage-gated channel, shaker-related subfamily, member 5
  • cow(508960) potassium voltage-gated channel, shaker-related subfamily, member 5
  • domestic cat(101100573) potassium voltage-gated channel, shaker-related subfamily, member 5
  • dog(403995) potassium voltage-gated channel, shaker-related subfamily, member 5
  • chicken(395115) potassium voltage-gated channel, shaker-related subfamily, member 5
  • naked mole-rat(101715453) potassium voltage-gated channel, shaker-related subfamily, member 5
  • domestic guinea pig(100732253) potassium voltage-gated channel, shaker-related subfamily, member 5
  • Domestic Rabbit(100008684) potassium voltage-gated channel, shaker-related subfamily, member 5
  • sheep(101111448) potassium voltage-gated channel, shaker-related subfamily, member 5

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-KCNA5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Monoclonal Anti-KCNA5 antibody produced in mouse, clone S7-45, 1 mg/mL, purified immunoglobulin,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-Potassium Channel Kv1.5 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reactividad de especies
mouse, rat
Aplicación
western blot

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
Guanidina hydrochloride, for molecular biology, ≥99%,
Especie
human
Guanidina hydrochloride, ≥98%,
Especie
human
Guanidina hydrochloride, organic base and chaeotropic agent, ≥99% (titration),
Especie
human
Guanidina hydrochloride, ,
Especie
human
Guanidine hydrochloride solution, Colorless liquid, 7.8 - 8.3 M, pH- 4.5 - 5.5,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human KCNA5,
Especie
human