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Merck

ELAVL1

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)

Sinónimos:
ELAV1, HUR, Hua, MelG
Especie:
ID UniProtKB:
ID del gen:
  • Human(1994) Summary: The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]
  • Mouse(15568) ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
  • Rat(363854) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • Domestic Rabbit(100353220) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • Horse(100060819) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • Zebrafish(30736) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • dog(611201) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • naked mole-rat(101713794) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • domestic cat(101094402) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • domestic guinea pig(100735972) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • sheep(100307040) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • chicken(395637) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
  • cow(617316) ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
RIPAb+ HuR Conjunto de anticuerpos y cebadores validados para RIP, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
RIP
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-phospho HuR (Ser221) Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
xenopus, bovine, chicken, human, mouse, porcine
Aplicación
inhibition assay
western blot
Anti-HuR Antibody, Upstate®, from rabbit,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-HuR/ELAVL1 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-ELAVL1 antibody produced in mouse, clone 4G8, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Elavl1,
Especie
mouse
MISSION® esiRNA, targeting human ELAVL1,
Especie
human