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Merck

CYP24A1

cytochrome P450, family 24, subfamily A, polypeptide 1

Sinónimos:
CP24, CYP24, HCAI, P450-CC24
Especie:
Human CYP24A1 (1591), Mouse Cyp24a1 (13081), Rat Cyp24a1 (25279), chicken CYP24A1 (395827), dog CYP24A1 (485935), domestic cat CYP24A1 (101096141), cow CYP24A1 (540080), Zebrafish cyp24a1 (100004700)
ID UniProtKB:
Q07973, Q15807, Q32ML3
ID del gen:
  • Human(1591) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(13081) cytochrome P450, family 24, subfamily a, polypeptide 1
  • Rat(25279) cytochrome P450, family 24, subfamily a, polypeptide 1
  • chicken(395827) cytochrome P450, family 24, subfamily A, polypeptide 1
  • dog(485935) cytochrome P450, family 24, subfamily A, polypeptide 1
  • domestic cat(101096141) cytochrome P450, family 24, subfamily A, polypeptide 1
  • cow(540080) cytochrome P450, family 24, subfamily A, polypeptide 1
  • Zebrafish(100004700) cytochrome P450, family 24, subfamily A, polypeptide 1

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Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
HPA022261
Anti-CYP24A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
HPA063771
Anti-CYP24A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
ABN201
Anti-CYP24A1 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
WH0001591M7
Monoclonal Anti-CYP24A1 antibody produced in mouse, clone 1F8, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
SAB6012016
Anti CYP24A1 Antibody, clone 23GB3795, Rabbit Monoclonal, clone 23GB3795, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reactividad de especies
human, rat
Aplicación
flow cytometry
immunofluorescence
western blot

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
K1003
Ketoconazole, 99.0-101.0% (EP, titration), meets EP testing specifications,
Especie
mouse, human, rat

esiRNA

Número de producto
Descripción
Especie
EHU002561
MISSION® esiRNA, targeting human CYP24A1,
Especie
human