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Merck

CASP6

caspase 6, apoptosis-related cysteine peptidase

Sinónimos:
MCH2
Especie:
ID UniProtKB:
ID del gen:
  • Human(839) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(12368) caspase 6
  • Rat(83584) caspase 6
  • dog(487899) caspase 6, apoptosis-related cysteine peptidase
  • Zebrafish(552927) caspase 6, apoptosis-related cysteine peptidase
  • chicken(395477) caspase 6, apoptosis-related cysteine peptidase
  • naked mole-rat(101707090) caspase 6, apoptosis-related cysteine peptidase
  • domestic guinea pig(100713360) caspase 6, apoptosis-related cysteine peptidase
  • cow(538409) caspase 6, apoptosis-related cysteine peptidase
  • sheep(101119820) caspase 6, apoptosis-related cysteine peptidase
  • domestic cat(768261) caspase 6, apoptosis-related cysteine peptidase

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
ANTI-PHOSPHO-CASPASE 6(S257) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-CASP6 (Cleaved-Asp162) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
mouse, rat
Aplicación
ELISA
immunohistochemistry

western blot
Anti-CASP6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-CASP6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-phospho-Caspase 6 (pSer257) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
N-Acetyl-Val-Glu-Ile-Asp-al, ~99% (HPLC), powder,
Especie
human
Caspase Inhibitor, ,
Especie
human
NSCI, ≥97% (HPLC), solid,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human CASP6,
Especie
human
MISSION® esiRNA, targeting mouse Casp6,
Especie
mouse