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Merck

BMPR2

bone morphogenetic protein receptor, type II (serine/threonine kinase)

Sinónimos:
BMPR-II, BMPR3, BMR2, BRK-3, PPH1, T-ALK
Especie:
ID UniProtKB:
ID del gen:
  • Human(659) Summary: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008]
  • Mouse(12168) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • Rat(140590) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • cow(407127) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • naked mole-rat(101701138) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • Domestic Rabbit(100350246) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • sheep(101103793) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • domestic guinea pig(100736232) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • chicken(374147) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • sheep(100294556) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • domestic cat(101096338) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • dog(478875) bone morphogenetic protein receptor, type II (serine/threonine kinase)

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ELISA

Referencia del producto
Descripción
Especie
Human BMPR-II ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-BMPR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-BMPR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-BMR2 Antibody, clone 3F6, ascites fluid, clone 3F6, from mouse,
Reactividad de especies
human, monkey, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-BMPR2 antibody produced in mouse, clone 3F6, ascites fluid,
Reactividad de especies
human, monkey, mouse, rat
Aplicación
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-BMPR2 antibody produced in mouse, clone 4A2, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA

Proteins

Referencia del producto
Descripción
Especie
BMPR2 (174-end), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human BMPR2,
Especie
human
MISSION® esiRNA, targeting mouse Bmpr2,
Especie
mouse