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Merck

AGT

angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

Sinónimos:
ANHU, SERPINA8
Especie:
Human AGT (183), Mouse Agt (11606), Rat Agt (24179), Thale Cress AGT (815822), Zebrafish agt (322485), fruit fly agt (40816), chicken AGT (421543), dog AGT (403783), domestic cat AGT (101093714), cow AGT (527114) ...Más
ID UniProtKB:
P01019, Q16358, Q16359, Q96F91
ID del gen:
  • Human(183) Summary: The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]
  • Mouse(11606) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • Rat(24179) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • Thale Cress(815822) alanine--glyoxylate aminotransferase
  • Zebrafish(322485) angiotensinogen
  • fruit fly(40816) O-6-alkylguanine-DNA alkyltransferase
  • chicken(421543) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • dog(403783) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • domestic cat(101093714) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • cow(527114) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • sheep(101119440) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • sheep(100294599) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • naked mole-rat(101717217) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • domestic guinea pig(100724950) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

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ELISA

Referencia del producto
Descripción
Especie
RAB0010
Angiotensin II EIA Kit, for serum, plasma, culture supernatant and cell lysates,
Especie
human
RAB1021
Human Angiotensinogen ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
MAB4051
Anticuerpo anti-enzima conversora de la angiotensina, clon 9B9, clone 9B9, Chemicon®, from mouse,
Reactividad de especies
feline, hamster, human, monkey, rat
Aplicación
ELISA
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
HPA001557
Anti-AGT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
ZRB1021
Anti-Angiotensinogen Antibody, clone 1B12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
SAB1405438
Anti-AGT antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
SAB1403532
Monoclonal Anti-AGT antibody produced in mouse, clone 3C10, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry
western blot

Proteins

Referencia del producto
Descripción
Especie
A9525
Angiotensina II humana, ≥93% (HPLC), powder,
Especie
human
A9650
Angiotensin I human acetate salt hydrate, ≥90% (HPLC), powder, suitable for mammalian cell culture,
Especie
human
A9202
Angiotensin Fragment 1-7 acetate salt hydrate, ≥90% (HPLC), powder,
Especie
human
176870
Angiotensinogen, Human Plasma, Native angiotensinogen from human plasma that is cleaved by renin to generate angiotensin I. It is a part of the renin-angiotensin system that regulates blood pressure and fluid balance.,
Especie
human
A2562
Angiotensinogen from human plasma, ≥80% (SDS-PAGE), lyophilized powder,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EHU131721
MISSION® esiRNA, targeting human AGT,
Especie
human