SML2614

Carboprost tromethamine

≥98% (HPLC)

• Synonym(s): Carboprost trometamol, (15S)-15-methyl prostaglandin F2α tromethamine, (5Z,9a,11a,15E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid tris(hydroxymethyl)aminomethane salt, (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-15- methylprosta-5,13-dien-1-oic acid with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1), Carboprost tromethamine
• Empirical Formula (Hill Notation): C₂₅H₄₇NO₈
• CAS Number: 58551-69-2
• Molecular Weight: 489.64
• MDL number: MFCD01694769
• UNSPSC Code: 12352116
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D 18 to 24°, c = 1.0 in chloroform-d
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 2 mg/mL, clear
• storage temp.: −20°C
• SMILES string: NC(CO)(CO)CO.O[C@H]1[C@H](C([C@H](C1)O)\C=C/[C@@](O)(CCCCC)C)C\C=C\CCCC(=O)O
• InChI: 1S/C21H36O5.C4H11NO3/c1-3-4-9-13-21(2,26)14-12-17-16(18(22)15-19(17)23)10-7-5-6-8-11-20(24)25;5-4(1-6,2-7)3-8/h5,7,12,14,16-19,22-23,26H,3-4,6,8-11,13,15H2,1-2H3,(H,24,25);6-8H,1-3,5H2/b7-5+,14-12-;/t16-,17?,18+,19-,21-;/m0./s1
• InChI key: UMMADZJLZAPZAW-QFXCEMDRSA-N

Description

Biochem/physiol Actions

Carboprost tromethamine is a metabolically stable synthetic analog of prostaglandin F2α. It is used clinically to treat severe postpartum bleeding and for the termination of pregnancy in the second trimester.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable