Kaurenoic acid (KA) is a diterpene which displays selective antibacterial activity against Gram-positive bacteria. Kaurenoic acid exhibits uterine relaxant activity via calcium blockade and opening ATP-sensitive potassium channels.
Chinese journal of natural medicines, 15(8), 625-630 (2017-09-25)
The kaurenoic acid-type diterpenoids in Acanthopanacis Cortex have been reported to be the major active components. However, the diterpenoids are present as position isomers that exacerbate the challenges in obtaining standards compounds. Little work has been done on the quantitative
Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(8-9), 677-682 (2011-01-08)
This study investigates the anti-inflammatory effects of a diterpenoid, kaurenoic acid, isolated from the root of Aralia continentalis (Araliaceae). To determine its anti-inflammatory effects, LPS-induced RAW264.7 macrophages were treated with different concentrations of kaurenoic acid and carrageenan-induced paw edema mice
Effect of the kaurenoic acid on genotoxicity and cell cycle progression in cervical cancer cells lines.
Silvia Maria Machado da Rocha et al.
Toxicology in vitro : an international journal published in association with BIBRA, 57, 126-131 (2019-03-02)
Physiology and molecular biology of plants : an international journal of functional plant biology, 24(5), 767-779 (2018-08-29)
Stevia rebaudiana is an important source of natural steviol glycosides and is of increasing interest in various fields of study. Therefore, understanding the molecular processes regulating its metabolism is of great importance. In this study, the stability of seven reference
Steviol glycosides such as stevioside have attracted the attention of the food and beverage industry. Recently, efforts were made to produce these natural sweeteners in microorganisms using metabolic engineering. Nonetheless, the steviol titer is relatively low in metabolically engineered microorganisms
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