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Key Documents

SAB1408077

Sigma-Aldrich

Anti-SYT16 antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

Synonym(s):

CHR14SYT, SYT14L, Strep14, syt14r, yt14r

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50 μG
€368.00

€368.00

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50 μG
€368.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

€368.00

Please contact Customer Service for Availability

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~22.8 kDa

species reactivity

human

technique(s)

western blot: 1 μg/mL

NCBI accession no.

BC040924

UniProt accession no.

Q17RD7

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SYT16(83851)

General description

Mouse polyclonal antibody raised against a full-length human SYT16 protein.
SYT16 (synaptotagmin XVI) is a putative membrane trafficking protein belonging to the synaptotagmin (Syt) gene family. It is composed of a single N-terminal transmembrane domain and a putative fatty-acylation region adjacent to the transmembrane domain.

Immunogen

SYT16 (AAH40924.1, 1 a.a. ~ 203 a.a) full-length human protein.

Sequence
MTRERMMGEKLFYLSHLHPEGEMKVTLVLEPRSNISSGGSPLSPSAVSHSDSTSSTQSLSHGGAPELLVGLSYNATTGRLSVEMIKGSHFRNLAVNRAPDTYGKLFLLNSVGQEMSRCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLMISVYNRRTMKRKEMIGWIALGQNSSGEEEQDHWEEMKETKGQQICRWHTLLES

Application

Anti-SYT16 antibody produced in mouse is suitable for wstern blot analysis.

Biochem/physiol Actions

The activity of SYT16 (synaptotagmin XVI) is dependent on the Ca(2+) similar to all the members of Syt family proteins. It forms Ca(2+) independent oligomer. It may be involved in membrane and vesicular trafficking in specific tissues outside the brain.

Physical form

Solution in phosphate buffered saline, pH 7.4

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
09023

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Mitsunori Fukuda
Journal of biochemistry, 133(5), 641-649 (2003-06-13)
Synaptotagmins (Syts) represent a large family of putative membrane trafficking proteins found in various species from different phyla. In this study, I identified a novel class of Syt (named Syt XIV) conserved from Drosophila to humans and its highly related
M Craxton
Genomics, 77(1-2), 43-49 (2001-09-07)
I used TBLASTn to probe DNA sequence databases with a consensus peptide sequence corresponding to the most highly conserved region of the rodent synaptotagmin (Syt) gene family, which is within the C2B domain. I found human homologues for all known

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