RAB0447

Phospho-Stat3 (pTyr⁷⁰⁵) and pan-Stat3 ELISA Kit

for detection of phospho-stat3 (pTyr⁷⁰⁵) and pan-stat3 in human, mouse or rat cell and tissue lysates

• NACRES: NA.32
• UNSPSC Code: 41116158
• Gene information: human ... STAT3(6774) ; mouse ... STAT3(20848) ; rat ... STAT3(25125)
• Species reactivity: human, mouse, rat
• Storage temp.: −20°C
• Shipped in: wet ice

Properties

• species reactivity: human, mouse, rat
• technique(s): ELISA: suitable, capture ELISA: suitable
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... STAT3(6774) ; mouse ... STAT3(20848) ; rat ... STAT3(25125)

Description

General description

Signal transducers and activators of transcription 3 (STAT3) is a transcription factor that belongs to the family of STAT proteins. The protein contains an Src homology 2 (SH2) domain for protein-protein interactions. STAT3 is activated by phosphorylation on tyrosine 705 by c-Jun N-terminal kinases (JNKs), cytokine receptor-associated kinases, nonreceptor tyrosine kinases, and growth factor receptor tyrosine kinases, in response to growth factors and cytokines. Phosphorylation of STAT3 is important for dimer formation and gene expression. STAT3 mediates the expression of a variety of genes that are involved in cell proliferation and differentiation. It also aids in pro-cancer immunity. The Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA (enzyme-linked immunosorbent assay) is a very rapid, convenient, and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.

The Phospho-Stat3 (pTyr⁷⁰⁵) ELISA (Enzyme-Linked Immunosorbent Assay) kit is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.

Immunogen

Stat3 (pTyr⁷⁰⁵) synthetic phosphopeptide, Recombinant Human Stat3

Application

Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA Kit has been used in enzyme-linked immunosorbent assay (ELISA) for quantitative measurement of phosphorylated signal transducer and activator of transcription3 (p-STAT3) in liver tissues.

Safety Information

• Pictograms: GHS05
• Signal Word: Warning
• Hazard Codes: H290
• Precautionary Statements: P234 - P390
• Hazard Classifications: Met. Corr. 1
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• Storage Class: 12 - Non Combustible Liquids