PLA0236

Anti-KRAS Antibody

from rabbit

• Synonym(s): ERK, ERK-2, ERK2, ERT1, MAP kinase 1, MAP kinase 2, MAP kinase isoform p42, MAPK 1, MAPK 2, MAPK2, P42MAPK, PRKM1, PRKM2, extracellular signal-regulated kinase 2, mitogen-activated protein kinase 2, p38, p40, p41, p41mapk, p42-MAPK, protein tyrosine kinase ERK2
• UNSPSC Code: 12352203
• NACRES: NA.41
• Species reactivity: human, mouse
• Technique(s): immunohistochemistry: 1:500- 1:2,000, western blot: 1:2,000- 1:10,000
• Application: IHC, WB
• Citations: -

Properties

• Product Name: Rabbit anti-ERK2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.
• biological source: rabbit
• Quality Segment: 100
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• species reactivity: human, mouse
• technique(s): immunohistochemistry: 1:500- 1:2,000, western blot: 1:2,000- 1:10,000
• accession no.: NP_002736.3
• shipped in: wet ice
• storage temp.: 2-8°C
• Gene Information: rabbit ... ERK2(5594)

Description

Immunogen

The epitope recognized by PLA0236 maps to a region between residue 310 and 360 of human extracellular signal-regulated kinase-2 (mitogen-activated protein kinase 1) using the numbering given in entry NP_002736.3 (GeneID 5594).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

Extracellular signal-regulated kinase 2 (ERK2/p42) is also known as mitogen-activated protein kinase 1 (MAPK1). ERK2 is part of a signal transduction pathway that begins with the small GTPase Ras and continues through a cascade of protein kinases that include Raf and MEK. Activation of this signaling pathway influences many cellular processes such as proliferation, differentiation and survival. ERK2 is very similar in sequence to ERK1/p44 and the activities of both ERK1 and ERK2 are usually considered together as total ERK activity. More recent evidence has shown that ERK1 and ERK2 are not functionally redundant and may have very different and specific roles.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable