P3868
Monoclonal Anti-Placenta Growth Factor antibody produced in mouse
clone 37203.111, purified immunoglobulin, lyophilized powder
Synonym(s):
Anti-PIGF
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500 μG
€959.00
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500 μG
€959.00
About This Item
Immunogen
purified recombinant human placenta growth factor expressed in E. coli.
Biochem/physiol Actions
Placental growth factors (PlGF) are involved in the growth, migration and survival of endothelial cells. All the four isoforms identified are expressed in placenta and umbilical vein endothelial cells. PlGF binds to specific Flt-1 receptors that result in activation and recruitment of dendritic cells, smooth muscle cells and inflammatory cells. PlGF2 has the ability to bind heparin while PlGF1 is a soluble isoform.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Valeria Tarallo et al.
American journal of cancer research, 1(2), 265-274 (2011-10-05)
Angiogenesis is one of the crucial events for cancer development and growth and vascular endothelial growth factor (VEGF) family plays an essential role in this biological phenomenon. The members of VEGF family mainly involved in angiogenesis are VEGF-A, VEGF-B and
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