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O5501

Sigma-Aldrich

Oxyphenonium bromide

Synonym(s):

2-([Cyclohexylhydroxyphenylacetyl]oxy)-N,N-diethyl-N-methylethanaminium bromide

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About This Item

Linear Formula:
C21H34NO3Br
CAS Number:
50-10-2
Molecular Weight:
428.40
EC Number:
200-010-7
MDL number:
MFCD00050259
UNSPSC Code:
12161900
PubChem Substance ID:
24898019
Pricing and availability is not currently available.

description

cationic

Assay

>98% (TLC)

mol wt

428.40 g/mol

SMILES string

Br.CC[N](C)(CC)CCOC(=O)C(O)(C1CCCCC1)c2ccccc2

InChI

1S/C21H34NO3.BrH/c1-4-22(3,5-2)16-17-25-20(23)21(24,18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6,8-9,12-13,19,24H,4-5,7,10-11,14-17H2,1-3H3;1H

InChI key

JKJFWDDPBNHJPV-UHFFFAOYSA-N

Application

Oxyphenonium bromide has been used in a study to assess masking mechanisms of bitter taste of drugs. [1] It has also been used in a study to investigate stoichiometric and microenvironmental effects on hydrolysis of propantheline in cyclodextrin solutions. [2]

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
044F0691

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[Use of endoscopic drug block of the vagus nerve and cryotherapy in the treatment of peptic ulcer].
V A Grushko et al.
Klinichna khirurhiia, (8)(8), 12-13 (1996-01-01)
T P Berezina et al.
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 91(8), 893-902 (2005-10-29)
In experiments on unanaesthetized rabbits, myoelectric activity (contractile activity index) of distal ileum, caecum, and proximal colon in two sites was studied under stress induced by fastening a rabbit to the table in supine position. The stress caused sharp decrease
T Joseph et al.
Arzneimittel-Forschung, 47(7), 869-872 (1997-07-01)
The effect of a combination of 150 mg tinidazole (CAS 19387-91-8) and 1 mg oxyphenonium bromide (CAS 50-10-2), referred to as the combination, was examined in various animal species to assess its safety. In mice and rats, the combination in
G I Nezhinskaia et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (2)(2), 12-13 (2007-09-29)
Effects of methacine, hexamethonium and their combinations with neostigmine on activity of B-lymphocytes in various phases of immune response and development of stress ulcers induced in animals were studied. The drugs were found to modulate B-lymphocyte activity for 28 days
Noriaki Funasaki et al.
Chemical & pharmaceutical bulletin, 54(8), 1155-1161 (2006-08-02)
The masking mechanisms of the bitter taste of propantheline bromide (PB) and oxyphenonium (OB) bromide by native and modified cyclodextrins, saccharides, surfactants, organic acids, nonionic and anionic polymers, and other compounds were investigated with ion selective electrodes. The intensity of
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