1-Naphthyl phosphate monosodium salt monohydrate has been used as a non-specific phosphatase inhibitor in the splice correction assay in HeLa pLuc 705 cells.[1]
Preferred substrate for bioanalytical determinations of acid phosphatases, such as prostatic acid phosphatase.
Biochem/physiol Actions
Non-specific phosphatase inhibitor. Inhibits acid, alkaline and protein phosphatases.
The analysis of damage products as biomarkers of inflammation has been hampered by a poor understanding of the chemical biology of inflammation, the lack of sensitive analytical methods and a focus on single chemicals as surrogates for inflammation. To overcome
Signal transducer and activator of transcription 3 (STAT3) is a key mediator of leukocyte differentiation and proliferation. The 3' end of STAT3 transcripts is subject to two alternative splicing events. One results in either full-length STAT3α or in STAT3β, which
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(4), 1383-1394 (2015-01-01)
The phosphoinositide-dependent signal transduction pathway has been implicated in the control of a variety of biologic processes, such as the regulation of cellular metabolism and homeostasis, cell proliferation and differentiation, and apoptosis. One of the key players in the regulation
Biochimica et biophysica acta, 1847(6-7), 587-598 (2015-04-07)
Mitochondria play a key role in adaptation during stressing situations. Cardiolipin, the main anionic phospholipid in mitochondrial membranes, is expected to be a determinant in this adaptive mechanism since it modulates the activity of most membrane proteins. Here, we used
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