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Key Documents

L3377

Sigma-Aldrich

Leu-D-Leu

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About This Item

Empirical Formula (Hill Notation):
C12H24N2O3
CAS Number:
Molecular Weight:
244.33
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

form

solid

technique(s)

HPLC: suitable
mass spectrometry (MS): suitable

storage temp.

−20°C

SMILES string

CC(C)C[C@H](N)C(=O)N[C@H](CC(C)C)C(O)=O

InChI

1S/C12H24N2O3/c1-7(2)5-9(13)11(15)14-10(12(16)17)6-8(3)4/h7-10H,5-6,13H2,1-4H3,(H,14,15)(H,16,17)/t9-,10+/m0/s1

InChI key

LCPYQJIKPJDLLB-VHSXEESVSA-N

Application

Leu-D-Leu may be used as a reference peptide in the development of separation and detection technologies such as CE-ESI-MS.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Hongzhi Ye et al.
Electrophoresis, 31(20), 3400-3406 (2010-09-30)
In this article, an approach has been developed for the analysis of some small peptides with similar pI values by CE-ESI-MS based on the online concentration strategy of dynamic pH junction. The factors affected on the separation, detection and online
Joachim Vater et al.
Rapid communications in mass spectrometry : RCM, 23(10), 1493-1498 (2009-04-08)
An innovative technique to investigate the intermediates involved in the biosynthesis of the lipoheptapeptide surfactin from Bacillus subtilis OKB105 combining whole-cell matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) with targeted generation of knock-out mutants was demonstrated. This method allows efficient
J A Vizcaíno et al.
Fungal genetics and biology : FG & B, 43(4), 234-246 (2006-02-10)
The generation of a wide ESTs library and database from Trichoderma harzianum CECT 2413 was the base for identifying the gene ThPTR2, coding for a PTR family di/tri-peptide transporter. The deduced protein sequence of the ThPTR2 gene showed the conserved
Y K Cho et al.
The Journal of biological chemistry, 273(38), 24305-24308 (1998-09-12)
Porcine pepsin proteolysis of the hexapeptide Leu-Ser-p-nitro-Phe-Nle-Ala-Leu-OMe (where OMe = methoxy and Nle = norleucine) in the presence of dipeptide Leu-Leu synthesizes a new hexapeptide Leu-Ser-p-nitro-Phe-Leu-Leu. Contrary to transpeptidation kinetics of other proteases, which depend upon an acyl-enzyme intermediate, the
E Sublette et al.
Brain research, 599(1), 165-170 (1992-12-18)
Responses to opioids can be bimodal depending on the concentration of opioid used. For example, low concentrations (nM) enhance whereas higher concentrations (10-100 nM) inhibit the electrically evoked release of enkephalin from the myenteric plexus. The nature of the responsiveness

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