H2255
5-Hydroxyindole-3-acetic acid (dicyclohexylammonium) salt
crystalline, ≥98% (TLC)
Synonym(s):
5-HIAA
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About This Item
Empirical Formula (Hill Notation):
C10H9NO3 · C12H23N
CAS Number:
Molecular Weight:
372.50
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Pricing and availability is not currently available.
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Assay
≥98% (TLC)
form
crystalline
color
white
storage temp.
−20°C
SMILES string
C1CCC(CC1)NC2CCCCC2.OC(=O)Cc3c[nH]c4ccc(O)cc34
InChI
1S/C12H23N.C10H9NO3/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12;12-7-1-2-9-8(4-7)6(5-11-9)3-10(13)14/h11-13H,1-10H2;1-2,4-5,11-12H,3H2,(H,13,14)
InChI key
NIDSGTAJKGNSEN-UHFFFAOYSA-N
Biochem/physiol Actions
Major serotonin metabolite.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Exposure to fine particulate matter (PM2.5) could induce lung impairment aggravation. Moreover, endogenous substances are known to play a significant role in lung impairment. Therefore, the research objectives was to investigate the influence of PM2.5-induced lung impairment on the levels
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Brain research, 1666, 1-10 (2017-04-25)
Recent human brain imaging studies implicate dysregulation of monoamine oxidase-A (MAO-A), in particular in the prefrontal cortex (PFC) and anterior cingulate cortex (ACC), in the development of major depressive disorder (MDD). This study investigates the influence of four alterations underlying
Jurjen J Luykx et al.
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Animal studies have revealed seasonal patterns in cerebrospinal fluid (CSF) monoamine (MA) turnover. In humans, no study had systematically assessed seasonal patterns in CSF MA turnover in a large set of healthy adults. Standardized amounts of CSF were prospectively collected
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British journal of clinical pharmacology, 83(8), 1654-1667 (2017-02-06)
The safety, tolerability, pharmacokinetics (PK) and pharmacodynamics of single and multiple doses of a novel mGlu2 agonist were assessed in healthy males. In two, Phase 1 investigator- and subject-blind, placebo-controlled studies, oral doses of prodrug LY2979165 were evaluated: single doses
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