Skip to Content
Merck
All Photos(1)

Documents

G2761

Sigma-Aldrich

Gly-Pro-7-amido-4-methylcoumarin hydrobromide

dipeptidylpeptidase IV substrate

Synonym(s):

Gly-Pro-AMC

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C17H19N3O4 · HBr
CAS Number:
115035-46-6
Molecular Weight:
410.26
MDL number:
MFCD00152092
UNSPSC Code:
12352204
PubChem Substance ID:
24895103
NACRES:
NA.32

Assay

≥97% (TLC)

form

powder

solubility

water: 50 mg/mL, clear, colorless to light yellow

storage temp.

−20°C

SMILES string

Br.CC1=CC(=O)Oc2cc(NC(=O)[C@@H]3CCCN3C(=O)CN)ccc12

InChI

1S/C17H19N3O4.BrH/c1-10-7-16(22)24-14-8-11(4-5-12(10)14)19-17(23)13-3-2-6-20(13)15(21)9-18;/h4-5,7-8,13H,2-3,6,9,18H2,1H3,(H,19,23);1H/t13-;/m0./s1

InChI key

PASXTQMFJRHMLJ-ZOWNYOTGSA-N

Application

Gly-Pro-7-amido-4-methylcoumarin hydrobromide has been used as a substrate for determining the dipeptidylpeptidase IV (DPPIV) activity of the extract of Allophylus cominia Sw.

Substrates

Substrate for dipeptidylaminopeptidase IV.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Fluorescence assay of x-prolyl dipeptidyl-aminopeptidase activity with a new fluorogenic substrate.
T Kato et al.
Biochemical medicine, 19(3), 351-359 (1978-06-01)
In vitro anti-diabetic activity of flavonoids and pheophytins from Allophylus cominia Sw. on PTP1B, DPPIV, alpha-glucosidase and alpha-amylase enzymes
Semaan DG, et al.
Journal of Ethnopharmacology, 203, 39-46 (2017)
Sandy Theysgeur et al.
Molecules (Basel, Switzerland), 26(1) (2021-01-06)
Like their owners, dogs and cats are more and more affected by overweight and obesity-related problems and interest in functional pet foods is growing sharply. Through numerous studies, fish protein hydrolysates have proved their worth to prevent and manage obesity-related
Muhammed Majeed et al.
Journal of the science of food and agriculture, 100(2), 509-516 (2019-09-06)
Emblica officinalis, known as amla in Ayurveda, has been used as a folk medicine to treat numerous pathological conditions, including diabetes. However, the novel extract of E. officinalis fruit extract (amla fruit extract, AFE, Saberry®) containing 100 g kg-1 β-glucogallin along with

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service