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EMU201661

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Nell1

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TTTGAACTGGAGAGCAGTGGCCCAAGAGAAGAGATACGCTATCATTACATCCATGGCGGCAAGCCCAGGACTGAGGCCCTTCCCTACCGCATGGCCGATGGACAGTGGCACAAGGTCGCGCTGTCTGTGAGCGCCTCTCACCTCCTACTCCATGTCGACTGCAATAGGATTTATGAGCGTGTGATAGATCCTCCGGAGACCAACCTTCCTCCAGGAAGCAATCTATGGCTTGGGCAACGTAATCAAAAGCATGGCTTTTTCAAAGGAATCATCCAAGATGGCAAGATCATCTTCATGCCGAACGGCTTCATCACACAGTGCCCCAACCTAAATCGCACTTGCCCAACATGCAGTGATTTCCTGAGCCTGGTTCAAGGAATAATGGATTTGCAAGAGCTTTTGGCCAAGATGA

Ensembl | mouse accession no.

ENSMUSG00000055409

NCBI accession no.

NM_001037906

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... NELL1(338352) , Nell1(338352)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Claudio Raimondi et al.
The Journal of experimental medicine, 211(6), 1167-1183 (2014-05-28)
To enable new blood vessel growth, endothelial cells (ECs) express neuropilin 1 (NRP1), and NRP1 associates with the receptor tyrosine kinase VEGFR2 after binding the vascular endothelial growth factor A (VEGF) to enhance arteriogenesis. We report that NRP1 contributes to
Hong-Bo Pang et al.
Nature communications, 5, 4904-4904 (2014-10-04)
Neuropilins (NRPs) are trans-membrane receptors involved in axon guidance and vascular development. Many growth factors and other signalling molecules bind to NRPs through a carboxy (C)-terminal, basic sequence motif (C-end Rule or CendR motif). Peptides with this motif (CendR peptides)

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