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EMU014261

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Vipr1

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

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product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CAAGGATATGGCCCTCTTCAACAACGGGGAGACAGACCACTGCTCTGAGGCCTCGGTGAGCTGCAAGGCAGCAGTGGTTTTCTTCCAGTATTGCGTCATGGCCAACTTCTTCTGGCTGCTGGTCGAGGGCCTCTACCTACACACCCTGCTGGCCGTCTCCTTCTTCTCTGAGCGGAAGTACTTCTGGGGGTACATACTCATCGGCTGGGGAGTGCCCAGTGTGTTCATCATGATATGGACGATTGTCAGGATCCATTTTGAGGATTTCGGGTGCTGGGACACCATCATCAACTCCTCACTGTGGTGGATCATAAAGGGCCCCATCCTCATCTCCATCTTGGTGAACTTCATCCTGTTTATCTGCATCATCCGAATCCTGGTTCAGAAGCTACGGCCACCCGACATTGGGAAGAATGATAGCAGCCCA

Ensembl | mouse accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Triple-negative breast cancers (TNBCs) are highly aggressive cancers that lack targeted therapies. However, EGFR is frequently activated in a subset of TNBCs and represents a viable clinical target. Because the endocytic adaptor protein Endophilin A2 (SH3GL1/Endo II) has been implicated
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PloS one, 10(7), e0132655-e0132655 (2015-07-24)
Melanomas cause over 76% of skin cancer deaths annually. Phosphatidylinositol 3-kinase (PI3K)-AKT-mammalian target of rapamycin (mTOR) signaling pathway is important for melanoma initiation and progression. In the current study, we evaluated the potential anti-melanoma effect of VS-5584, a novel and
Alexandre K Rouquette-Jazdanian et al.
PloS one, 10(6), e0131823-e0131823 (2015-06-30)
Linker for Activation of T cells (LAT) is an adapter protein that is essential for T cell function. Knock-in mice with a LAT mutation impairing calcium flux develop a fatal CD4+ lymphoproliferative disease. miR-155 is a microRNA that is correlated

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