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C9140

Sigma-Aldrich

Convallatoxin

≥65%

Synonym(s):

3β,5α,14-Trihydroxy-19-oxo-5β,20(22)-cardenolide 3-(6-deoxy-α-L-mannopyranoside), Strophanthidin α-L-rhamnopyranoside

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About This Item

Empirical Formula (Hill Notation):
C29H42O10
CAS Number:
508-75-8
Molecular Weight:
550.64
EC Number:
208-086-3
MDL number:
MFCD00069477
UNSPSC Code:
12352200
PubChem Substance ID:
24893136
NACRES:
NA.77

form

powder

concentration

≥65%

SMILES string

C[C@@H]1O[C@@H](O[C@H]2CC[C@]3(C=O)[C@H]4CC[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)C6=CC(=O)OC6)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C29H42O10/c1-15-22(32)23(33)24(34)25(38-15)39-17-3-8-27(14-30)19-4-7-26(2)18(16-11-21(31)37-13-16)6-10-29(26,36)20(19)5-9-28(27,35)12-17/h11,14-15,17-20,22-25,32-36H,3-10,12-13H2,1-2H3/t15-,17-,18+,19-,20+,22-,23+,24+,25-,26+,27-,28-,29-/m0/s1

InChI key

HULMNSIAKWANQO-JQKSAQOKSA-N

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Biochem/physiol Actions

A cardiac glycoside found in lily-of-the-valley with digitalis-like cardiac effects.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301 + H311 + H331

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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[Changes in the toxicity of certain cardiovascular drugs as a result of hyperbaric oxygenation].
K M Reznikov
Farmakologiia i toksikologiia, 44(3), 342-346 (1981-05-01)
[Effect of corglycon and cavinton on the hemodynamics of patients with initial manifestations of insufficiency of cerebral circulation].
M M Ishchenko et al.
Vrachebnoe delo, (5)(5), 53-55 (1988-05-01)
S B Frantsuzova et al.
Farmakologiia i toksikologiia, 43(6), 674-679 (1980-11-01)
The effect of convallotoxin on hemodynamics of the right and left ventricles and pressure in the pulmonary artery was studied in intact dogs and in surgical stenosis of the pulmonary trunk. In intact anesthetized dogs, convallotoxin produced changes in hemodynamics
[Effect of corglycon and vasoactive agents on systemic and cerebral hemodynamics in cerebral infarct].
S M Vinichuk
Vrachebnoe delo, (7)(7), 28-32 (1987-07-01)
[Use of physicochemical analytical methods for assessing the interaction of various drug forms in therapeutic practice].
M N Tsarevskaia et al.
Farmakologiia i toksikologiia, 49(5), 42-44 (1986-09-01)
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