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C199

CGS-15943

≥98% (HPLC), Adenosine receptor antagonist, solid

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Synonym(s):

9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine

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Size/SKUAvailabilityPrice
25 mg
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€154.00

About This Item

Empirical Formula (Hill Notation):
C13H8ClN5O
CAS Number:
Molecular Weight:
285.69
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
solid

€154.00

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Product Name

CGS-15943, solid

assay

≥98% (HPLC)

Quality Segment

form

solid

color

white

solubility

DMSO: >10 mg/mL, H2O: insoluble

storage temp.

room temp

SMILES string

Nc1nc2ccc(Cl)cc2c3nc(nn13)-c4ccco4

InChI

1S/C13H8ClN5O/c14-7-3-4-9-8(6-7)12-17-11(10-2-1-5-20-10)18-19(12)13(15)16-9/h1-6H,(H2,15,16)

InChI key

MSJODEOZODDVGW-UHFFFAOYSA-N

Application

CGS-15943 has been used as a non-selective adenosine receptor antagonist to study its effects on the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and hepatocellular carcinoma (HCC). It has also been used as a non-selective adenosine receptor antagonist to investigate the mechanism underlying adenosine inhibition on cholangiocarcinoma (CCA) cells.

Biochem/physiol Actions

CGS-15943 is a potent and non-selective adenosine receptor antagonist. It exhibits anti-carcinogenic and anti-apoptotic activity.

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This Item
S4568S6451M228
description

solid

description

≥98% (HPLC), solid

description

≥98% (HPLC)

description

solid

form

solid

form

solid

form

powder

form

solid

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

room temp

storage temp.

-

storage temp.

2-8°C

storage temp.

-

solubility

H2O: insoluble, DMSO: >10 mg/mL

solubility

DMSO: soluble >10 mg/mL, H2O: insoluble

solubility

DMSO: ≥20 mg/mL

solubility

2-hydroxypropyl-β-cyclodextrin: insoluble, DMSO: 2 mg/mL, ethanol: insoluble, H2O: insoluble

color

white

color

off-white

color

light tan to tan

color

white


PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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