A0476

Activin Receptor-Like Kinase 1/Fc Chimera human

>90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

• Synonym(s): ALK-1
• UNSPSC Code: 51111800
• NACRES: NA.32
• MDL number: MFCD03702792
• Biological source: human
• Recombinant: expressed in NSO cells
• Assay: >90% (SDS-PAGE)
• Form: lyophilized powder
• Mol wt: 50-55 kDa by SDS-PAGE (reducing), calculated mol wt ~37.3 kDa
• Impurities: endotoxin, tested

Properties

• biological source: human
• Quality Segment: 100
• recombinant: expressed in NSO cells
• assay: >90% (SDS-PAGE)
• form: lyophilized powder
• mol wt: 50-55 kDa by SDS-PAGE (reducing), calculated mol wt ~37.3 kDa
• packaging: pkg of 100 μg
• storage condition: avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• UniProt accession no.: P37023
• storage temp.: −20°C
• Gene Information: human ... ACVRL1(94)

Description

Biochem/physiol Actions

ALK-1 is a type I complex of the serine/threonine kinases. Type I and II receptors bind ligands in the TGF-β superfamily. Human and mouse ALK-1 share approximately 71% amino acid sequence identity in their extracellular domains.

Type I complex of the serine/threonine kinases; bind ligands in the TGF-β superfamily.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Analysis Note

Can be used as a calibrator for ALK-1 antibodies.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)