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47641

Sigma-Aldrich

Folin & Ciocalteu′s phenol reagent

2 M (with respect to acid)

Synonym(s):

Folin-Ciocalteu phenolic solution

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100 ML
€46.80
500 ML
€107.00

€46.80

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100 ML
€46.80
500 ML
€107.00

About This Item

MDL number:
MFCD00132625
UNSPSC Code:
12161503
NACRES:
NA.25

€46.80

Please contact Customer Service for Availability
Request a Bulk Order

Quality Level

200

concentration

2 M (with respect to acid)

density

1.27 g/mL at 20 °C

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Application

Folin & Ciocalteu′s phenol reagent has been used in the estimation of total phenolic and flavonoids contents in plant samples[1], tomato extracts[2], subcanopy tree species[3] and fermented grape skins.[4]

Other Notes

Reagent for the determination of total protein[5]

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H290,H314

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM6053
BCCM5629
BCCK8300
BCCJ5962
BCCH3316

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Surface functionalization of bioactive glasses with natural molecules of biological significance, part II: Grafting of polyphenols extracted from grape skin
Zhang X, et al.
Applied Surface Science, 287(5), 341-348 (2013)
Alterations of vitamin C, total phenolics, and antioxidant capacity as affected by processing tomatoes to different products
Gahler S, et al.
Journal of Agricultural and Food Chemistry, 51(27), 7962-7968 (2003)
Cyanogenesis in the Australian tropical rainforest endemic Brombya platynema (Rutaceae): chemical characterisation and polymorphism
Miller RE, et al.
Functional plant biology, 33(5), 477-486 (2006)
Determination of total protein.
G L Peterson
Methods in enzymology, 91, 95-119 (1983-01-01)
Mechanism & inhibition kinetics of bioassay-guided fractions of Indian medicinal plants and foods as ACE inhibitors
Khan MY and Kumar V
Journal of traditional and complementary medicine (2018)
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Questions

1–4 of 4 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Which Folin-Coicalteau Regent is suitable for determination of total phenolic content in plant extracts?

    1 answer

    1. Unfortunately, there is no Folin-Coicalteu's reagent available that is specifically tested and recommended for use with plant tissue. However, this product has been cited in several publications for determining the phenolic content in various plant types. Suitability would have to be determined by the end user. Please see the links below to review this publications:
      https://www.sciencedirect.com/science/article/pii/S2225411018300130
      https://pubs.acs.org/doi/10.1021/jf034743q
      https://www.publish.csiro.au/fp/fp05305
      https://www.researchgate.net/publication/259874665_Surface_functionalization_of_bioactive_glasses_with_natural_molecules_of_biological_significance_part_II_Grafting_of_polyphenols_extracted_from_grape_skin

      Please see the following link to review the product datasheet:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/288/844/47641dat.pdf

      Helpful?

  4. Which Follin-ciocalteu reagent is suitable for detection of Phenolic content in fermented beverages?

    1 answer

    1. Folin & Ciocalteu's phenol reagent has been used for the estimation of total phenolic and flavonoids contents in fermented beverages. Please refer to this article, https://www.sciencedirect.com/science/article/pii/S0169433213018151

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