21882

5(6)-Carboxy-2′,7′-dichlorofluorescein

BioReagent, suitable for fluorescence, ≥95% (TLC)

• Empirical Formula (Hill Notation): C₂₁H₁₀Cl₂O₇
• CAS Number: 111843-78-8
• Molecular Weight: 445.21
• MDL number: MFCD00037452
• UNSPSC Code: 12352108
• PubChem Substance ID: 57647948
• NACRES: NA.32

Properties

• product line: BioReagent
• Quality Level: 100
• Assay: ≥95% (TLC)
• form: solid
• pKa: 5.1
• mp: ≥250 °C (lit.)
• solubility: DMF: soluble; DMSO: soluble; H₂O: soluble (pH ≥ 5)
• fluorescence: λ_ex 504 nm; λ_em 529 nm in 0.1 M Tris pH 8.0
• suitability: suitable for fluorescence
• SMILES string: OC(=O)c1ccc(c(c1)C(O)=O)C2=C3C=C(Cl)C(=O)C=C3Oc4cc(O)c(Cl)cc24.OC(=O)c5ccc(C(O)=O)c(c5)C6=C7C=C(Cl)C(=O)C=C7Oc8cc(O)c(Cl)cc68
• InChI: 1S/2C21H10Cl2O7/c22-13-4-11-17(6-15(13)24)30-18-7-16(25)14(23)5-12(18)19(11)10-3-8(20(26)27)1-2-9(10)21(28)29;22-13-4-11-17(6-15(13)24)30-18-7-16(25)14(23)5-12(18)19(11)9-2-1-8(20(26)27)3-10(9)21(28)29/h2*1-7,24H,(H,26,27)(H,28,29)
• InChI key: WHFHRELKGQJJBQ-UHFFFAOYSA-N

Description

Application

5(6)-Carboxy-2′,7′-dichlorofluorescein may be used as a specific substrate/probe to study the identity, activity and specificity of multidrug resistance protein 2 (MRP2) molecules.

suitable as pH-indicator

Other Notes

Fluorescent intracellular pH indicator in the pH 4-5 range

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves