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13110

Sigma-Aldrich

N-Benzoyl-L-tyrosine ethyl ester

≥98.0% (NT)

Synonym(s):

BTEE

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About This Item

Linear Formula:
4-(HO)C6H4CH2CH(NHCOC6H5)CO2C2H5
CAS Number:
3483-82-7
Molecular Weight:
313.35
Beilstein:
2223819
EC Number:
222-469-2
MDL number:
MFCD00002388
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
329750011

Product Name

N-Benzoyl-L-tyrosine ethyl ester, ≥98.0% (NT)

Assay

≥98.0% (NT)

form

powder or crystals

optical activity

[α]20/D −26±3°, c = 1% in ethanol

color

white

mp

118-121 °C (lit.)
118-122 °C

solubility

methanol: 1 g/10 mL, clear, colorless to almost colorless (















)

SMILES string

CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c2ccccc2

InChI

1S/C18H19NO4/c1-2-23-18(22)16(12-13-8-10-15(20)11-9-13)19-17(21)14-6-4-3-5-7-14/h3-11,16,20H,2,12H2,1H3,(H,19,21)/t16-/m0/s1

InChI key

SRLROPAFMUDDRC-INIZCTEOSA-N

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General description

N-Benzoyl-L-tyrosine ethyl ester (BTEE) is a substrate which is completely resistant to trypsin and is required for the assay of chymotrypsin.[1]

Application

N-Benzoyl-L-tyrosine ethyl ester has been used for measuring chymotrypsin activity.[2][3]

Other Notes

Substrate, completely resistant to trypsin, for the assay of chymotrypsin[4][5][6]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBP2997V
BCBN1442V

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K N Rao et al.
Analytical biochemistry, 65(1-2), 548-551 (1975-05-12)
K.A. Walsh et al.
Methods in Enzymology, 19, 31-31 (1979)
F Chen et al.
Biochemical and biophysical research communications, 214(3), 839-846 (1995-09-25)
In this report the differential regulation of NF-kappa B and nitric oxide (NO) was investigated in the mouse macrophage cell line RAW 264.7 following exposure to a mineral dust (silica) and/or an endotoxin (Lipopolysaccharide, LPS). The results indicated that silica
F Chen et al.
Biochemical and biophysical research communications, 214(3), 985-992 (1995-09-25)
In this report, we demonstrate that NF-kappa B, a ubiquitous transcription factor, plays an essential role in silica-induced inflammatory mediator production in the mouse macrophage cell line RAW 264.7. Compared to the effect of lipopolysaccharide (LPS), silica mediated a stronger
Guilbault GG
Enzymatic Methods of Analysis: International Series of Monographs in Analytical Chemistry (201)
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