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B1143000

Bromazepam

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

7-Bromo-5-(2-pyridyl)-3H-1,4-benzodiaxepin-2(1H)-one

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About This Item

Empirical Formula (Hill Notation):
C14H10BrN3O
CAS Number:
1812-30-2
Molecular Weight:
316.15
MDL number:
MFCD00057902
UNSPSC Code:
41116107
PubChem Substance ID:
329773169
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

bromazepam

manufacturer/tradename

EDQM

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

O=C(CN=C1C2=CC=CC=N2)NC3=C1C=C(Br)C=C3

InChI

1S/C14H10BrN3O/c15-9-4-5-11-10(7-9)14(17-8-13(19)18-11)12-3-1-2-6-16-12/h1-7H,8H2,(H,18,19)

InChI key

VMIYHDSEFNYJSL-UHFFFAOYSA-N

Gene Information

human ... GABRA2(2555)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Bromazepam EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Yvan Gaillard et al.
Forensic science international, 207(1-3), e16-e18 (2011-01-05)
We reported on the death by poisoning of a one-month-old baby that had followed the death of one of her sister (due to cyamemazine overdose). Exhumation of the corpse was done 8 months after burial and revealed the presence of
M S Attia
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 74(4), 972-976 (2009-09-29)
A rapid, simple and sensitive spectrofluorimetric method for determination of trace amount of bromazepam is developed. In phosphate buffer of pH 7.4. The bromazepam enhance the luminescence intensity of the Eu(3+) ion in Eu(3+)-bromazepam complex at lambda(ex)=390nm. The produced luminescence
Laura Wainstein et al.
International clinical psychopharmacology, 26(1), 54-62 (2010-10-01)
France has one of the highest recorded rates of psychotropic use of drugs compared with other European countries, especially for anxiolytics, hypnotics and antidepressants. The aim of this study was to characterize the use of three psychotropic drugs among the
Marlo Cunha et al.
Neuroscience letters, 448(1), 33-36 (2008-10-22)
The aim of this study was to investigate the influence of bromazepam on EEG and the motor learning process when healthy subjects were submitted to a typewriting task. We investigated bromazepam due to its abuse by various populations and its
Marlo Cunha et al.
Arquivos de neuro-psiquiatria, 67(2A), 214-218 (2009-06-24)
This study aimed to elucidate cortical mechanisms and to identify the areas where occur such mechanisms due to interaction between bromazepam and motor learning. The sample was composed of 45 healthy subjects randomly distributed in 3 groups: placebo (n=15), bromazepam
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