81292
Poly(ethylene glycol)
analytical standard, for GPC, 4,000
Synonym(s):
PEG
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grade
analytical standard
for GPC
Quality Level
shelf life
limited shelf life, expiry date on the label
mol wt
Mn ~4120
Mp ~4450
Mw ~4240
technique(s)
gel permeation chromatography (GPC): suitable
Mw/Mn
~1.03
application(s)
cleaning products
cosmetics
food and beverages
personal care
format
neat
storage temp.
2-8°C
SMILES string
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
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General description
Poly(ethylene glycol) (PEG) is regarded as the gold standard for stealth polymers in polymer based drug delivery. PEGs and their anionic or non-ionic derivatives are widely used in cosmetic products.
Application
PEG is known to modify enzymes and proteins for the preparation of improved therapeutic agents.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Safety assessment on polyethylene glycols (PEGs) and their derivatives as used in cosmetic products.
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Bioconjugate chemistry, 4(5), 314-318 (1993-09-01)
Monomethoxypolyethylene glycol (mPEG) of average molecular weight 5000 was transformed in a series of synthetic steps to a new activated form of PEG, a stable thiol-protected intermediary, for reaction with cysteine residues in proteins under mild conditions to produce PEG--protein
Poly (ethylene glycol) in drug delivery: pros and cons as well as potential alternatives.
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Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
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Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro
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