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34127

Supelco

Patulin solution

100 μg/mL in acetonitrile, analytical standard

Synonym(s):

4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one, PAT

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About This Item

Empirical Formula (Hill Notation):
C7H6O4
CAS Number:
149-29-1
Molecular Weight:
154.12
EC Number:
200-835-2
MDL number:
MFCD00005858
UNSPSC Code:
85151701
PubChem Substance ID:
329754833
NACRES:
NA.24

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

SMILES string

OC1OCC=C2OC(=O)C=C12

InChI

1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2

InChI key

ZRWPUFFVAOMMNM-UHFFFAOYSA-N

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General description

Patulin is an important mycotoxin produced by several species of mold, especially within Penicillium, Aspergillus and Byssochlamys. It is commonly found in fruits especially apples, pears and grapes.
Patulin is a mycotoxin produced by several mold species. It has been found in fruit, especially apples, fruit juice, cider and stewed fruits. Because of its highly toxic properties, this compound has been the focus of many studies.

Application

Patulin solution may be used as an analytical reference standard for the determination of the analyte in:
  • dried apple rings using high-performance liquid chromatography with diode array detection (HPLC-DAD)(1)
  • fruit juices using high-performance liquid chromatography with diode array detection (HPLC-DAD) and gas chromatography coupled to mass spectrometry (GC-MS)(2)

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM3685
BCCL6494
BCCL3590
BCCL0709
BCCK7134

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HPLC-DAD method for the determination of patulin in dried apple rings.
Katerere RD, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 19(4), 389-392 (2008)
S Hatab et al.
Journal of applied microbiology, 112(5), 892-899 (2012-03-08)
Apples and apple products are the most notably commodities contaminated with patulin (PAT), which cause detrimental effects on human health and economic problems. The primary objective of this study was to investigate the removal of PAT contamination from apple juice
Assunta Raiola et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(9), 3068-3072 (2012-06-13)
Apple juices and purees represent categories widely consumed by whole population and above all children. Patulin (PAT) is a mycotoxin known for its acute and chronic effects in animals. Several studies indicate there is a risk associated to the PAT
Alicia Rodríguez et al.
International journal of food microbiology, 155(1-2), 10-18 (2012-02-14)
A multiplex real-time PCR (qPCR) method to quantify aflatoxin, ochratoxin A (OTA) and patulin producing molds in foods was developed. For this, the primer pairs F/R-omt, F/R-npstr and F/R-idhtrb and the TaqMan probes, OMTprobe, NPSprobe and IDHprobe targeting the omt-1
Eszter Horváth et al.
Acta biologica Hungarica, 63(3), 389-398 (2012-09-12)
The effects of the mycotoxin patulin on the thermodynamics and kinetics of the transition of bovine serum albumin (BSA) in aqueous solution were studied by Differential Scanning Calorimetry and Photoluminescence methods. Results show that in the presence of patulin, the
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Protocols

Selective Extraction and Cleanup of Patulin Mycotoxin from Apple Juice Samples

This selective and fast MIP extraction procedure allows trace amounts of patulin to be easily detected in apple juice, with high analyte recovery and reproducibility.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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