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AP127

Sigma-Aldrich

Goat Anti-Mouse IgG Antibody, Fc

2.4 mg/mL, Chemicon®

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.46

biological source

goat

Quality Level

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

clone

polyclonal

species reactivity

mouse

manufacturer/tradename

Chemicon®

concentration

2.4 mg/mL

technique(s)

ELISA: suitable
immunoprecipitation (IP): suitable
western blot: suitable

shipped in

wet ice

target post-translational modification

unmodified

General description

Immunoglobulin G (IgG), is one of the most abundant proteins in human serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.

Application

Detect Mouse IgG using this Goat anti-Mouse IgG Antibody, Fc validated for use in ELISA, IP & WB.

Physical form

Affinity purified immunoglobulin. Liquid. Buffer = 0.01% Sodium Phosphate, 0.25 M NaCl, pH 7.6

Storage and Stability

Store at +2-8°C in undiluted aliquots for up to six months, sterile conditions.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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S Eadmusik,C Molette,H Remignon,X Fernandez
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The efficacy of chimeric antigen receptor (CAR) T cell therapy against poorly responding tumors can be enhanced by administering the cells in combination with immune checkpoint blockade inhibitors. Alternatively, the CAR construct has been engineered to coexpress factors that boost
Miles C Scotcher et al.
PloS one, 5(6), e11047-e11047 (2010-06-16)
Botulinum neurotoxin (BoNT), the causative agent of botulism, a serious neuroparylatic disease, is produced by the anaerobic bacterium Clostridium botulinum and consists of a family of seven serotypes (A-H). We previously reported production of high-affinity monoclonal antibodies to BoNT serotype
Larry H Stanker et al.
Toxins, 5(11), 2212-2226 (2013-11-21)
Botulism is a serious foodborne neuroparalytic disease, caused by botulinum neurotoxin (BoNT), produced by the anaerobic bacterium Clostridium botulinum. Seven toxin serotypes (A-H) have been described. The majority of human cases of botulism are caused by serotypes A and B
Larry H Stanker et al.
Journal of immunology (Baltimore, Md. : 1950), 185(1), 729-737 (2010-06-10)
Prion diseases are fatal, neurodegenerative illnesses caused by the accumulation of PrP(Sc), an aberrantly folded isoform of the normal, cellular prion protein. Detection of PrP(Sc) commonly relies on immunochemical methods, a strategy hampered by the lack of Abs specific for

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