8.43443

Heptafluorobutyric acid

for synthesis

• Synonym(s): Heptafluorobutyric acid
• Empirical Formula (Hill Notation): C₄HF₇O₂
• CAS Number: 375-22-4
• Molecular Weight: 214.04
• MDL number: MFCD00004171
• UNSPSC Code: 12352106
• EC Index Number: 206-786-3
• NACRES: NA.22

Properties

• vapor pressure: 13.3 hPa ( 25 °C)
• Quality Level: 200
• Assay: ≥98.0% (acidimetric)
• form: liquid
• pH: 1 (20 °C in H₂O)
• bp: 121 °C/1013 mbar
• mp: -17.5 °C
• density: 1.65 g/cm³ at 20 °C
• storage temp.: 2-30°C
• InChI: 1S/C4HF7O2/c5-2(6,1(12)13)3(7,8)4(9,10)11/h(H,12,13)
• InChI key: YPJUNDFVDDCYIH-UHFFFAOYSA-N

Description

Application

• Heptafluorobutyric acid in peptide modification analysis: A study discussed the application of heptafluorobutyric acid in the retention time prediction for post-translationally modified peptides. This research facilitates the analysis of phosphorylated peptides in biological samples, enhancing the accuracy and efficiency of proteomic studies (Battellino et al., 2024).
• Environmental monitoring of perfluorinated compounds: Heptafluorobutyric acid was used in a method involving in-source fragmentation for the identification of perfluoropentanoic acid and perfluorobutanoic acid in environmental matrices and human serum. This application highlights its role in environmental health studies and pollution monitoring (Yu et al., 2023).
• Synthesis and adsorption studies: Heptafluorobutyric acid is highlighted in the synthesis and evaluation of spherical amino-functionalized covalent organic frameworks for the adsorption of perfluorinated compounds. This illustrates its importance in the development of materials aimed at environmental remediation (Ye et al., 2023).

Analysis Note

Assay (acidimetric): ≥ 98.0 %
Identity (IR): passes test

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1A
• Storage Class Code: 8B - Non-combustible, corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable