444219-M

MMP-1 Substrate III, Fluorogenic

An excellent quenched fluorescence substrate for MMP-1.

• Synonym(s): MMP-1 Substrate III, Fluorogenic
• Empirical Formula (Hill Notation): C₅₁H₇₂N₁₄O₁₂S
• Molecular Weight: 1105.27
• UNSPSC Code: 12352200

Properties

• Quality Level: 100
• Assay: ≥94% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: yellow
• solubility: 50% acetic acid: soluble
• fluorescence: λ_ex ~365 nm; λ_em ~450 nm
• storage temp.: −20°C

Description

General description

An excellent quenched fluorescence substrate for MMP-1. Has a better k_cat/K_m value than the MMP Substrate (Cat. No. 444207).

Quenched fluorescence substrate for MMP-1 (excitation maximum: 365 nm; emission maximum: 450 nm). Has a better k_cat/K_m value than the MMP-Substrate (Cat. No. 444207).

Biochem/physiol Actions

Primary Target
Quenched fluorescence substrate for MMP-1

Warning

Toxicity: Standard Handling (A)

Sequence

DNP-Pro-Cha-Abu-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH₂[Cha = β-cyclohexylalanyl; Abu = L-α-aminobutyryl; Abz = 2-aminobenzoyl]

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

McGeehan, G.M., et al. 1994. J. Biol. Chem.269, 32814.
Green, M., et al. 1992. Medicinal Chemistry Annual Meeting, poster (Abstr. 41).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable