235752
Anti-C-Reactive Protein Rabbit pAb
liquid, Calbiochem®
Synonym(s):
Anti-CRP
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
form
liquid
contains
≤0.1% sodium azide as preservative
species reactivity
human
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CRP(1401)
General description
Rabbit polyclonal antibody purified by DEAE anion exchange chromatography. Recognizes C-reactive protein.
Recognizes C-reactive protein. Does not exhibit cross-reactivity against normal human serum.
Immunogen
purified, human CRP
Application
ELISA (see application references)
Immunoblotting (0.1 µg/ml,see application references)
Immunoprecipitation (see comments)
Radioimmunoassay (see comments)
Immunoblotting (0.1 µg/ml,see application references)
Immunoprecipitation (see comments)
Radioimmunoassay (see comments)
Packaging
Please refer to vial label for lot-specific concentration.
Warning
Toxicity: Standard Handling (A)
Physical form
In 100 mM NaCl, 15 mM phosphate buffer, pH 7.2-7.4.
Other Notes
Exhibits a single precipitin line against CRP control serum. Does not exhibit cross-reactivity against normal human serum. The optimal dilution for RIA and immunoprecipitation should be determined for each sample type. Antibody should be titrated for optimal results in individual systems.
Ridker, P.M., et al. 1997. N. Engl. J. Med.336, 973.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Donald N Ngwa et al.
Frontiers in immunology, 11, 586669-586669 (2020-10-30)
C-reactive protein (CRP) binds to several species of bacterial pathogens including Streptococcus pneumoniae. Experiments in mice have revealed that one of the functions of CRP is to protect against pneumococcal infection by binding to pneumococci and activating the complement system.
Maurice Swinkels et al.
Scientific reports, 8(1), 1643-1643 (2018-01-28)
Retinal inflammation plays a key role in the progression of age-related macular degeneration (AMD), a condition that leads to loss of central vision. The deposition of the acute phase pentraxin C-reactive protein (CRP) in the macula activates the complement system
Asmita Pathak et al.
Frontiers in immunology, 11, 1780-1780 (2020-08-28)
The aim of this study was to test the hypothesis that C-reactive protein (CRP) protects against the development of atherosclerosis and that a conformational alteration of wild-type CRP is necessary for CRP to do so. Atherosclerosis is an inflammatory cardiovascular
Anika Alberts et al.
Frontiers in immunology, 11, 596103-596103 (2020-12-29)
Endogenous and exogenous crystalline structures are involved in various pathologies and diseases in humans by inducing sterile inflammation, mechanical stress, or obstruction of excretory organs. The best studied of these diseases is gout, in which crystallization of uric acid in
Anika Alberts et al.
Scientific reports, 10(1), 6391-6391 (2020-04-15)
Gout is caused by crystallization of uric acid in the form of monosodium urate (MSU) crystals, which induce a sterile inflammatory response that is hardly distinguishable from microbe-induced inflammatory responses. It is unclear, if MSU crystals (like microbes) are recognized
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