203392

(+)-Blebbistatin

The inactive enantiomer of (±)-Blebbistatin.

• Synonym(s): (+)-Blebbistatin
• Empirical Formula (Hill Notation): C₁₈H₁₆N₂O₂
• CAS Number: 1177356-70-5
• Molecular Weight: 292.33
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• color: yellow
• solubility: methanol: 1.5 mg/mL; 100% DMSO: 100 mg/mL; 90% DMSO: 75 mg/mL
• shipped in: wet ice
• storage temp.: −20°C
• InChI: 1S/C18H16N2O2/c1-12-7-8-15-14(11-12)16(21)18(22)9-10-20(17(18)19-15)13-5-3-2-4-6-13/h2-8,11,22H,9-10H2,1H3/t18-/m0/s1
• InChI key: LZAXPYOBKSJSEX-SFHVURJKSA-N

Description

General description

The inactive enantiomer of (±)-Blebbistatin (Cat. No. 203390). Useful as a negative control for the active enantiomer (Cat. No. 203391).

The inactive enantiomer of (±)-Blebbistatin (Cat. No. 203390). Also useful as a negative control for the more active enantiomer (-)-Blebbistatin (Cat. No. 203391).

Biochem/physiol Actions

Cell permeable: no

Primary Target
Inactive enantiomer of (±)-Blebbistatin

Product does not compete with ATP.

Reversible: no

Packaging

Packaged under inert gas

Warning

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

Reconstitution

Following reconstitution in methanol, aliquot and freeze (-20°C). Stock solutions in 90% DMSO or methanol are stable for up to 1 month at -20°C. Stock solutions in 100% DMSO are unstable; reconstitute just prior to use.

Other Notes

Shu, S., et al. 2005. Proc. Natl. Acad. Sci. USA102, 1472.
Jacobelli, J., et al. 2004. Nat. Immunol.5, 531.
Kovacs, M., et al. 2004. J. Biol. Chem.279, 35557.
Straight, A.F., et al. 2003. Science299, 1743.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable