189488

Autophagy Regulators Panel

A panel containing 23 cell-permeable, potent, and selective small molecule regulators that is useful for the study of autophagy process.

• UNSPSC Code: 12352200

Properties

• Quality Level: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; protect from light
• shipped in: wet ice
• storage temp.: −20°C

Description

General description

A panel containing 23 cell-permeable, potent, and selective small molecule regulators that is useful for the study of autophagy process. The panel contains the molecules listed in the table and 15 ml of anhydrous DMSO.

A panel containing 23 cell-permeable, potent, and selective small molecule regulators that is useful for the study of autophagy process:10 mg of Leupeptin, Hemisulfate, Synthetic (Cat. No. 108976),1 mg of AMPK Inhibitor, Compound C (Cat. No. 171260),50 mg of Autophagy Inhibitor, 3-MA (Cat. No. 189490),10 mg of Autophagy Inducer, STF-62247 (Cat. No. 189497),10 µg of Bafilomycin A1, Streptomyces griseus (Cat. No. 196000),10 mg of bpV(phen) (Cat. No. 203695)10 mg of Dynamin Inhibitor I, Dynasore (Cat. No. 324410),10 mg of DAPK Inhibitor (Cat. No. 324788),1 mg of HDAC Inhibitor XXIII, Tubastatin A (Cat. No. 382187),5 mg of mTOR Inhibitor III, PP242 (Cat. No. 475988),5 mg of Necrostatin-1 (Cat. No. 480065),5 mg of Nigericin, Sodium Salt, Streptomyces hygroscopicus (Cat. No. 481990),10 mg of Nocodazole (Cat. No. 487928),10 mg of Pifithrin-μ (Cat. No. 506155),1 mg of PI-103 (Cat. No. 528100),1 mg of Rapamycin (Cat. No. 553210),5 mg of PIKfyve Inhibitor (Cat. No. 524611),10 mg of SMER28 (Cat. No. 573121),5 mg of Tamoxifen, 4-Hydroxy-, (Z)- (Cat. No. 579002),1 mg of Thapsigargin (Cat. No. 586005)1 mg of Caspase Inhibitor I, Z-VAD-fmk (Cat. No. 627610),and 10 mg of Tunicamycin, Streptomyces lysosuperficus (Cat. No. 654380), and1 mg of Wiskostatin (Cat. No. 681525).Also provided with 15 ml of anhydrous DMSO (Cat. No. KP31817). Supplied with a data sheet.

Also available separately: Spautin-1 (Cat. No. 567569)

Packaging

Packaged under inert gas

Warning

Toxicity: Multiple Toxicity Values, refer to MSDS (O)

Reconstitution

Please refer to information provided on the CD for reconstitution of individual inhibitors.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Fleming, A., et al. 2011. Nat. Chem. Biol.7, 9.
Mizushima, N. and Levine, B., 2010. Nat. Cell Biol.12, 823.
Klionsky, D.J., et al. 2010. Autophagy6, 1017.
Mizushima, N., et al. 2010. Cell140, 313.
Zhang, L., et al. 2007. Proc. Natl. Acad. Sci. USA104, 19023.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): 188.6 °F - (refers to pure substance)
• Flash Point(C): 87 °C - (refers to pure substance)