Skip to Content
Merck
All Photos(1)

Documents

CF0043

Sigma-Aldrich

3,5-Bis(trifluoromethyl)benzyl azide

Synonym(s):

1-(Azidomethyl)-3,5-bis(trifluoromethyl)benzene

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C9H5F6N3
CAS Number:
620533-92-8
Molecular Weight:
269.15
UNSPSC Code:
12352125
NACRES:
NA.06

Quality Level

100

SMILES string

[N-]=[N+]=NCC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1

InChI

1S/C9H5F6N3/c10-8(11,12)6-1-5(4-17-18-16)2-7(3-6)9(13,14)15/h1-3H,4H2

InChI key

JKGHUBCPWOLOFQ-UHFFFAOYSA-N

General description

3,5-Bis(trifluoromethyl)benzyl azide is a fluoroalkyl azide reagent active in copper-catalyzed azide-alkyne cycloaddition (click reaction). In addition to its use as a highly fluorinated building block, it can also be functionalized onto biomolecules, advanced materials, or polymers containing an alkyne. Its relative stability and number of magnetically equivalent fluorines make it a highly effective 19F NMR sensor for these and other materials.

Learn more about fluorinated click chemistry

Automate your fluorination reactions with Synple Automated Synthesis Platform (SYNPLE-SC002)

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

195.8 °F

Flash Point(C)

91 °C

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Fluorinated Azides: Click Chemistry Meets Fluorine

Fluorinated azides are a new tool that can be used to introduce fluorinated groups to molecules. These molecules can utilize click chemistry to easily add fluorinated groups.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service