96260
Z-Gly-Phe
≥99.0%
Synonym(s):
Z-glycyl-L-phenylalanine
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Linear Formula:
C6H5CH2OOCNHCH2CONHCH(CH2C6H5)COOH
CAS Number:
Molecular Weight:
356.37
Beilstein:
2182728
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22
Assay
≥99.0%
form
powder
optical activity
[α]20/D +40±1°, c = 2.5% in ethanol
reaction suitability
reaction type: solution phase peptide synthesis
mp
125-132 °C
application(s)
peptide synthesis
SMILES string
OC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)OCc2ccccc2
InChI
1S/C19H20N2O5/c22-17(12-20-19(25)26-13-15-9-5-2-6-10-15)21-16(18(23)24)11-14-7-3-1-4-8-14/h1-10,16H,11-13H2,(H,20,25)(H,21,22)(H,23,24)/t16-/m0/s1
InChI key
FLGYJBNDDWLTQR-INIZCTEOSA-N
Other Notes
Z-protected dipeptide employed in the Anteunis′ test to determine racemization in peptide coupling
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
G Kuznetsov et al.
The Journal of biological chemistry, 267(6), 3932-3939 (1992-02-25)
HepG2 cells were employed as model system to investigate potential relationships between early protein processing and Ca2+ storage by the endoplasmic reticulum. Ca2+ was required for glycoprotein processing and export by intact cells. The processing and export of alpha 1-antitrypsin
R A Firestone et al.
Journal of medicinal chemistry, 25(5), 539-544 (1982-05-01)
Bioactive primary and secondary amines, when acylated with the Z-Gly-Phe group, are transported into pinocytic cells, such as macrophages, P-815 mastocytoma, SV-40 3T3, and leukemia 1210, much faster than the parent compounds. Amines such as lysosomotropic detergents [R. A. Firestone
C D McCallum et al.
Biochemistry, 34(6), 1815-1824 (1995-02-14)
Many membrane functions are modulated by the bulk biophysical properties of the membrane. Various compounds which alter membrane physical properties were investigated for their ability to modulate insulin receptor autophosphorylation and signaling. Compounds which raise the bilayer to hexagonal phase
T J Wheeler
Biochimica et biophysica acta, 979(3), 331-340 (1989-03-13)
Three compounds which inhibit glucose transport in rat adipocytes have been proposed to act directly on the glucose transporter protein. We tested these proposals by examining the effects of the compounds on the stereospecific glucose uptake catalyzed by adipocyte membrane
M Roth et al.
Clinica chimica acta; international journal of clinical chemistry, 135(1), 65-71 (1983-11-30)
A method has been designed for the assay of pancreatic carboxypeptidase A in blood serum. It uses Z-Gly-Phe as the substrate and fluorimetric determination of the released phenylalanine in an amino acid analyser, which yields a measure of free carboxypeptidase
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service