641472

1-Boc-4-(aminomethyl)piperidine

97%

• Synonym(s): 1,1-Dimethylethyl 4-(aminomethyl)-1-piperidinecarboxylate, N-(tert-Butoxycarbonyl)-4-aminomethylpiperidine
• Empirical Formula (Hill Notation): C₁₁H₂₂N₂O₂
• CAS Number: 144222-22-0
• Molecular Weight: 214.30
• MDL number: MFCD01076207
• UNSPSC Code: 12352100
• PubChem Substance ID: 24883120
• NACRES: NA.22

Properties

• Assay: 97%
• refractive index: n20/D 1.473 (lit.)
• bp: 237-238 °C (lit.)
• density: 1.013 g/mL at 25 °C (lit.)
• SMILES string: CC(C)(C)OC(=O)N1CCC(CN)CC1
• InChI: 1S/C11H22N2O2/c1-11(2,3)15-10(14)13-6-4-9(8-12)5-7-13/h9H,4-8,12H2,1-3H3
• InChI key: KLKBCNDBOVRQIJ-UHFFFAOYSA-N

Description

Application

Precursor in the preparation of a variety of different protein agonists or antagonists including:

• Kinesin spindle protein inhibitors with potential anticancer activity
• Orphan G-protein coupled receptor GPR119 agonist with antidiabetic potential
• Pim-1 inhibitors
• Aspartic acid protease inhibitors

Reactant involved in enantioselective synthesis of N-alkyl terminal aziridines

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): No data available
• Flash Point(C): No data available
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves