597201

(Chloromethyl)trimethoxysilane

96%

• Linear Formula: (H₃CO)₃SiCH₂Cl
• CAS Number: 5926-26-1
• Molecular Weight: 170.67
• MDL number: MFCD00468107
• UNSPSC Code: 12352103
• PubChem Substance ID: 24881675
• NACRES: NA.23

Properties

• Assay: 96%
• bp: 151 °C (lit.)
• density: 1.132 g/mL at 25 °C (lit.)
• SMILES string: CO[Si](CCl)(OC)OC
• InChI: 1S/C4H11ClO3Si/c1-6-9(4-5,7-2)8-3/h4H2,1-3H3
• InChI key: FPOSCXQHGOVVPD-UHFFFAOYSA-N

Description

General description

Chloromethyltrimethoxysilane (CMTMS) is a trialkoxysilane with chloromethyl as the organofunctional group having hydrophobic characteristics. Chloromethyl is the electron withdrawing group that improves the mechanical properties of the molecule. CMTMS is mainly utilized as a silane based precursor material for the preparation of surface enhancement based coatings and other silane based products.

Application

CMTMS and its colloidal solution can be used in the development of aerogels. It can also be used in surface modification of silica nanoparticle for the fabrication of in vitro anticancer drug release system.

Chloromethyltrimethoxysilane may be used in the preparation of 1-methyl-1H-benzimidazole (MBI)-modified nanoparticles.{33} Mesoporous monolithic silica gels can also be prepared from Chloromethyltrimethoxysilane. {34}

Safety Information

• Pictograms: GHS02
• Signal Word: Danger
• Hazard Statements: H225
• Precautionary Statements: P210 - P233 - P240 - P241 - P242 - P243
• Hazard Classifications: Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 26.6 °F - closed cup
• Flash Point(C): -3 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves