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280216

Sigma-Aldrich

-Acetylglycinamide

97%

Synonym(s):

2-Acetamidoacetamide

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About This Item

Linear Formula:
CH3CONHCH2CONH2
CAS Number:
Molecular Weight:
116.12
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

97%

mp

140-143 °C (lit.)

SMILES string

CC(=O)NCC(N)=O

InChI

1S/C4H8N2O2/c1-3(7)6-2-4(5)8/h2H2,1H3,(H2,5,8)(H,6,7)

InChI key

WQELDIQOHGAHEM-UHFFFAOYSA-N

Application

-Acetylglycinamide (2-Acetamidoacetamide) was used in the preparation of 3-unsubstituted 2-pyridones by a tandem reaction with chalcones.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Tomohisa Nezu et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 32(5), 844-850 (2012-01-19)
Limited evidence exists on the relationships between severity of white-matter lesions (WMLs) and cerebral hemodynamics in patients without major cerebral artery disease. To examine changes of cerebral blood flow (CBF), oxygen metabolism, and vascular reserve capacity associated with severity of
V I Naumova et al.
Biulleten' eksperimental'noi biologii i meditsiny, 107(6), 711-713 (1989-06-01)
The effect of electroshock (ECS) and piracetam, oxiracetam or N-acetylglycinamide on the passive avoidance conditioned response in rats was studied. The antiemetic effect of the compounds was examined in cats as well. The results obtained allowed us to distinct the
Matthew Auton et al.
Biochemistry, 43(5), 1329-1342 (2004-02-06)
With knowledge of individual transfer free energies of chemical groups that become newly exposed on protein denaturation and assuming the group transfer free energy contributions are additive, it should be possible to predict the stability of a protein in the
[The systems analysis of the effect of piracetam, glycine and N-acetylglycinamide on long-term learning].
A I Machula et al.
Eksperimental'naia i klinicheskaia farmakologiia, 56(4), 55-57 (1993-07-01)
A Regioselective Tandem Reaction between Chalcones and 2-Acetamidoacetamide Promoted by Cs2 CO3 for the Preparation of 3-Unsubstituted 2-Pyridones.
Wang S, et al.
Synthesis, 2003(04), 0487-0490 (2003)

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