D4875

16-Dehydropregnenolone acetate

≥95%

• Synonym(s): 3β-Acetoxy-5,16-pregnadien-20-one, 3β-Hydroxy-5,16-pregnadien-20-one acetate, 5,16-Pregnadien-3β-ol-20-one acetate
• Empirical Formula (Hill Notation): C₂₃H₃₂O₃
• CAS Number: 979-02-2
• Molecular Weight: 356.50
• NACRES: NA.77
• PubChem Substance ID: 24893901
• UNSPSC Code: 12352202
• EC Number: 213-558-7
• MDL number: MFCD00051130
• Assay: ≥95%
• Form: powder
• Quality level: 100

Properties

• Quality Level: 100
• assay: ≥95%
• form: powder
• SMILES string: CC(=O)OC1CCC2(C)C3CCC4(C)C(CC=C4C(C)=O)C3CC=C2C1
• InChI: 1S/C23H32O3/c1-14(24)19-7-8-20-18-6-5-16-13-17(26-15(2)25)9-11-22(16,3)21(18)10-12-23(19,20)4/h5,7,17-18,20-21H,6,8-13H2,1-4H3
• InChI key: MZWRIOUCMXPLKV-UHFFFAOYSA-N

Description

Biochem/physiol Actions

16-Dehydropregnenolone acetate (DPA) is synthesized from steroids sapogenin, diosgenin and solasodine. 16-Dehydropregnenolone acetate (DPA) is a crucial intermediate for the synthesis of steroid hormones-based drugs. It is an antagonist for farnesoid X receptor (FXR) and modulates cholesterol metabolism. It is considered as a potential antihyperlipidemic agent. Chemically synthesized steroid derivatives from DPA have cytotoxic features and could serve as potential anticancer agents.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)