B9688

Pizotifen

≥98% (HPLC)

• Synonym(s): Pizotifen, Pizotyline; 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine
• Empirical Formula (Hill Notation): C₁₉H₂₁NS
• CAS Number: 15574-96-6
• Molecular Weight: 295.44
• EC Number: 239-632-9
• MDL number: MFCD00864192
• UNSPSC Code: 12352200
• PubChem Substance ID: 329773323
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• solubility: DMSO: ≥8 mg/mL
• originator: Novartis
• storage temp.: room temp
• SMILES string: CN1CCC(\CC1)=C2\c3ccccc3CCc4sccc24
• InChI: 1S/C19H21NS/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18/h2-5,10,13H,6-9,11-12H2,1H3
• InChI key: FIADGNVRKBPQEU-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Pizotifen is a Serotonin antagonist used for prophylaxis of migraine

Pizotifen is a serotonin antagonist acting mainly at the 5-HT1, 5-HT2A and 5HT2C receptors with some antihistamine activity. It is used for the prevention of vascular headache including migraine and cluster headache.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Warning
• Hazard Statements: H302,H361
• Precautionary Statements: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable